Arthur James » Psoriasis

We speak of Psoriasis

admin — Tue, 02 Dec 2008 07:29:03 +0000

The term psoriasis is called a complex range of expressions and clinical inflammatory iperproliferative genetically determined, typically but not necessarily involving the skin lesions with erythema with squamous-onset mainly in the II-III decade of life, of varying lengths (mostly Chronic) and unpredictable developments (mostly recidivist).
Clinical Definition
The clinical manifestations of psoriasis vary widely as to distinguish a bet or follicular, guttata, nummulare, a large spots, rupioide, elephant, pustular localized (palmar-plantar chronic, acute-foot palm, and continues acrodermatite forms extra-acrali localized generalized pustular psoriasis), generalized pustular (acute, and circini ring, child and youth), premenstrual pregnant, unstable, erythroderma, arthropathy (similreumatoide-symmetrical, arthritis-like mono-oligoartritica, interphalangeal, mutilating hands and feet , Axial spondilitica-sacroileitica, temporomandibolare, cervical-like arthritis, sternal). Arthropathy injuries are found in 6-34% of patients psoriasis.
Finally forms are distinguished characteristics of certain anatomical areas: the inverse psoriasis or folds a well-defined edges that look "painted", the sebopsoriasi, affecting areas seborroiche "and its genitals in childhood with the appearance of" napkin psoriasis, psoriasis of the penis, scalp, nail, mucous membranes, eye, palm plantar of the face and ear.
E ‘evident in the face of this broad and diversified spectrum of events, a major difficulty in defining clinically psoriasis. Therefore, especially to a useful prognostic evaluation and appropriate treatment choices, it tends to propose a clinical definition comprising five main forms: guttata psoriasis, chronic psoriasis in spots, pustular psoriasis, erythroderma psoriasis, psoriasis arthropathy.
These various clinical expressions seem to match specific genetic alterations that could make it possible to single out various syndromes in the very near future, pathogenetic mechanisms qualitatively or quantitatively different and, finally, different therapeutic approaches.
The possible therapeutic approaches are innumerable and sometimes very good, however, any treatment must be confronted with the problem of the chronic nature of this disorder and then with local side effects and systemic, acute and chronic.
How to deal
The treatment of psoriasis are divided into topical and systemic depending on whether the drug is used on the skin surface or systemic. In some cases may also be useful therapeutic approaches without drugs.
It is for the medical specialist in dermatology establish a proper treatment for psoriasis. Some treatments can only be ineffective, but many others are certainly dangerous and can even aggravate psoriasis itself if used for long or without correct information.

Treatment for skin diseases (psoriasis, eczema, dermatitis …)

admin — Tue, 02 Dec 2008 07:17:33 +0000

The waters of sulphurous of Porretta Terme, with their action cleaning of the skin from the surface layers of dead cells and stimulating the growth of deeper layers, are playing an important effect in the treatment of skin diseases (psoriasis, eczema, burns, forms allergic contact, etc.).

Psoriasis: doctor-patient dialogue

admin — Tue, 02 Dec 2008 07:13:55 +0000

A booklet, produced by Dr. Holy Dattoli, within which are handled all aspects of the relationship between psoriasis and the patient’s doctor: the first visit to applications to go to a specialist, sharing of information on diagnosis.

Psoriasis and social relations

admin — Tue, 02 Dec 2008 07:11:13 +0000

Cover Psoriasis and reports A social brochure, prepared by the Dr. Anna Lanzoni, within which are handled all aspects of the impact of psoriasis on social relationships. It also provided a series of practical recommendations to address and overcome the difficulties in interpersonal relationships that can occur in people with psoriasis.

How to treat psoriasis

admin — Tue, 02 Dec 2008 07:04:55 +0000

The psoriasis is a chronic disease subject to constant change, making it treatable but not guaribile. There are many therapeutic principals, designed to accelerate the disappearance of psoriatic spots, these drugs are very effective for some patients, less for others, there are also cases in which psoriasis heals spontaneously without pharmacological interventions.
In principle, however, the therapy should be adjusted to different extent and location of the disease, age, sex, severity of form and so on.
The choice of treatment should always be performed by a doctor, because some drugs can submit specific contraindications or determine serious side effects. In mild or moderate you prefer topical medications (local treatment), in the form of considerable scope and severity, we appeal to systemic therapies, often quite demanding. Both treatments local systemic ones go to cycles and not on an ongoing basis in order to reduce the risk of toxicity and side effects of a long-term treatment; suspension, especially in cases of systemic therapy, it should be implemented so gradually. Definitely recommended the use of moisturizing creams, which maintain the elasticity of the skin and help to eliminate or minimize microlesioni. Among the topical treatments must be made for products based pharmaceutics acetylsalicylic acid, in varying concentrations from 3% to 20%, or pitch, which facilitate the removal of scales and make the skin more elastic.
Much also used cortisone, in the form of lotions, creams, ointments, which also act on the inflammatory component, reduce the proliferation of keratinocytes (cytostatic action) and their action is usually rapid, but prolonged use may result in thinning skin all atrophy up; other drugs are represented by ointments based calcipotriol and tacalcitolo (analogues of vitamin D), which stimulate the proper maturation of the keratinocytes, without risk of significant side effects, and tazarotene, a retinoid (derivative vitamin A) used in gel 0.1%, particularly effective in mild and moderate forms, acting both as anti-inflammatory that normalizing the differentiation of skin cells.
The systemic therapy should be done with two major categories of drugs, retinoids and immunosuppressants. The only retinoid available orally is the acitretina, effective but toxic and reserved for more severe forms.
The immunosuppressive of choice are represented by methotrexate and cyclosporin, (the latter reserved for patients who did not respond or contraindications to the use of other therapies). Drugs are effective but have side effects sometimes very serious.
Often, when both local and systemic therapy is associated phototherapy, based on ultraviolet radiation type A and B (in particular the narrow-band UVB) with fluorescent lamps or halogen-metal, to be performed always under control doctor.

The symptoms of psoriasis

admin — Tue, 02 Dec 2008 06:59:17 +0000

The diagnosis of the disease should always be performed by a doctor.
The onset is usually gradual, with steps for improvement and other rapidly worsening. The lesions can cover each area of the body. In the most characteristic are as erythematous plaques or spots (red) well defined and covered with scales of silver white color of varying thickness.
They are generally in a symmetrical and, in relation to the location and form, determine many variations of the disease:
Psoriasis vulgaris – It ‘s the classic form, characterized by predilection for certain locations: the extensor surfaces of limbs, particularly elbows and knees, scalp, the loin-sacral region, the palms of the hands, feet plant, while the face is rarely affected. Usually occurs in the second or third decade of life.
Psoriasis eruptive or guttata – Comparsa eruption on the entire body surface, many chiazzette lenticular (guttata = shaped drop), which also face peeling, with savings on the face and scalp.
It affects mainly young people after streptococcal infection, usually tonsils, causing general malaise and pain in small joints.
Pustular psoriasis – It ‘s a rare form, the most severe, characterized by the appearance of numerous isolated pustules head of a pin on spotting erythematous. This form is unknown two varieties, mainly located in a palm-foot home (Barber) and widespread , more serious, which seriously undermines the overall condition of the patient with high fever, chills, sensations of burning, with imbalances idroelettrolitici hypoalbuminaemia.
Inverse psoriasis – Relatively frequently, has a location "reverse" compared to the classic, affecting the inguinal folds, axilliary, axilliary cables and elbows. The skin is intensely red, smooth, clear limitations, while the number of peeling is minimal or absent.
Erythroderma psoriasis – It ‘s the most severe; manifested with fever and involvement of the entire skin, which looks very flushed to the intense vascularization. The general state of the subject can be seriously compromised because of the temperature, dehydration and electrolyte imbalance, which is often encounter.
Sometimes psoriasis can affect the joints, especially those of the hands, feet, knees and femur. The onset is often subacute; may follow, precede or be simultaneous demonstrations skin. Psoriasis Arthropathy said, can be associated with onicopatia (nail disorder) and lead to severe joint deformities.

They were identified trigger factors of psoriasis?

admin — Tue, 02 Dec 2008 06:51:49 +0000

Many factors can be triggers that lead to the activation of the pathogenic process of psoriasis. We must, however, emphasize that the impact of incentives varies from subject to subject and that while it may be an aggravating factor for some, this manifests itself harmless to others.
Stress
Stress is a set of reactions that the brain triggers the body against a dramatic event that currency or dangerous to the health of the psycho-physical.
Stress is now recognized play an important role in the unleashing of psoriasis is the first event, either as aggravation of an already existing form.
The trauma
Any type of physical trauma, such as scratching, burns, surgical scars or accidental shocks, may result in susceptible humans, even at a distance of one or two weeks, the appearance of psoriasis spots, just after the premises concerned. Were described cases in which psoriasis was induced at the injection site of vaccination, or where they occurred sunburn and injuries from scratching. This phenomenon is known as "Koebner phenomenon." It seems that not only the intensity of an accidental blow, but the frequency with which it remains victims, is crucial for the development of psoriasis.
The Drugs
The drugs deserve special mention. Taking certain medications can be a trigger for psoriasis or worse, if already present.
- Lithium, used to treat manic-depressive disorders and other psychiatric disorders, psoriasis worsens in about half of patients with psoriasis who take. In every way you can ask your doctor to find an alternative treatment to lithium.
- Anti malarials such as chinacrina, the chloroquine or hydroxychloroquine may cause a re-ignition of psoriasis usually two or three weeks after the drug was taken. E ‘be noted that hydroxychloroquine has the lowest index of side effects.
- Beta blockers used in hypertension worsen psoriasis in approximately 25-30% of patients who take them regularly. However, it is not known whether all drugs used in hypertension, using this mechanism pharmacodynamic (beta-blockers), worsen psoriasis or whether it can have a potential to do so. Sometimes they can be replaced with other drugs that have a similar result.
- The indomethacin, a non-steroidal anti drug used in treatment of, it was noted worsen psoriasis. Even in this case can be chosen alternative medicines, although the effects it produces benefits that are far greater than its side effects, which can be minimized by proper use.
Infections
The infection not only on the skin but internal organs are important elements that can trigger a latent psoriasis. An example for all the tonsil infection that in a not insignificant percentage of individuals, leads to the unleashing or contribute to the maintenance of psoriasis. The infection, caused by streptococcus betaemolitico, is often linked to the appearance of eruptions psoriasis in children. For adults, on the occasion of this type of infection, there is an acute general of the disorder, accompanied by increased drug resistance.
Abnormal metabolism
The alteration of certain metabolic processes and poor nutrition are calcium in some cases responsible for the appearance of psoriasis.
Hormones
Often psoriasis appears at puberty and menopause, periods in which the biological balance is radically altered.
Ethyl alcohol and smoking
Severe forms of psoriasis are often accompanied from abuse of alcohol and nicotine.
Other less important factors unleashed can be represented by:
- Climate more or less dry, because it has an impact on the state of hydration of the skin;
- Diet, as was noticed a benefit when there are some improved dietary habits;
- Allergies, which are smaller stimuli but not to neglect in patients with a disease which is so influenced psoriasis.

WHO IS AT RISK smoke PSORIASIS

admin — Tue, 02 Dec 2008 06:40:31 +0000

Cigarettes increase the risk of psoriasis, can also become ill of psoriasis or seeing worsen the disease is much higher as many if they smoke. Even if you stop smoking, after 20 years the risk fall to revert to normal levels.
These results were obtained from a study conducted jointly by Canadian research of Vancouver general hospital and scientists of the Massachusetts General Hospital, Brigham and Women’s Hospital and Harvard School of Public Health in Boston.
In a period of 14 years were examined 116,608 women between 25 and 42 years and has found that smokers had a risk of falling ill of psoriasis by 78% higher compared to non smokers.
Moreover, the passive smoking in pregnancy or in infancy, also exposes the child to a high risk.
"These results – says Hyon K. says Hyon K. Choi, one of the authors of the study – as well as confirm the well-known risks of smoking, give an incentive to stop smoking for all those people who are at risk of psoriasis or already suffer from them. Yes saw it – ends – that stopping you can have a significant improvement in symptoms. "

Psoriasis in practice

admin — Tue, 02 Dec 2008 06:34:43 +0000

CariDee English, winner of the seventh edition of the popular TV show "America’s Next Top Model" joins the dermatologists – Dr. Wayne P. Gulliver and Professor. Martine Bagot – to ask the identification of better treatments for patients suffering from psoriasis as you. Through his personal testimony, Caridee want to help spread awareness of the seriousness of this disease by encouraging other patients to be aware to get the necessary help.
"Suffering from psoriasis since I very small and, in some periods, was affected 70% of my body," said Caridee. "Since receiving a biological treatment, my psoriasis has improved dramatically I would encourage other patients with psoriatic contact your doctor to know as much as possible the disease, ensuring that those who are receiving the best treatments are available."